By the end of this chapter, the reader should be able to:
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Distinguish between controversies that the evidence has substantially resolved and limitations that remain genuinely open
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Explain the Piccinini 2020 RCT findings and why their methodological context matters for interpretation
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Identify the structural limitations of the current evidence base and understand what further research is needed
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Respond to common objections about safety, efficacy, cost, and the quackery association with evidence-based answers